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Index > Protein center > VIPR2(Gene name) > Human
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  • VIPR2 (Gene name),
  • Vasoactive intestinal polypeptide receptor 2 (Protein name ),  VIPR2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    VIPR2(VIP2R);
    Protein name:
    Vasoactive intestinal polypeptide receptor 2(VIP-R-2);
    Alternative:
    Pituitary adenylate cyclase-activating polypeptide type III receptor(PACAP type III receptor;PACAP-R-3;PACAP-R3);Helodermin-preferring VIP receptor;VPAC2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    438
    Sequence:
    50:
    MRTLLPPALL | TCWLLAPVNS | IHPECRFHLE | IQEEETKCAE | LLRSQTEKHK | 
    100:
    ACSGVWDNIT | CWRPANVGET | VTVPCPKVFS | NFYSKAGNIS | KNCTSDGWSE | 
    150:
    TFPDFVDACG | YSDPEDESKI | TFYILVKAIY | TLGYSVSLMS | LATGSIILCL | 
    200:
    FRKLHCTRNY | IHLNLFLSFI | LRAISVLVKD | DVLYSSSGTL | HCPDQPSSWV | 
    250:
    GCKLSLVFLQ | YCIMANFFWL | LVEGLYLHTL | LVAMLPPRRC | FLAYLLIGWG | 
    300:
    LPTVCIGAWT | AARLYLEDTG | CWDTNDHSVP | WWVIRIPILI | SIIVNFVLFI | 
    350:
    SIIRILLQKL | TSPDVGGNDQ | SQYKRLAKST | LLLIPLFGVH | YMVFAVFPIS | 
    400:
    ISSKYQILFE | LCLGSFQGLV | VAVLYCFLNS | EVQCELKRKW | RSRCPTPSAS | 
    438:
    RDYRVCGSSF | SRNGSEGALQ | FHRGSRAQSF | LQTETSVI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    Pfam:
    KEGG:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human VIP-R-2
    Cat.:
    E15102h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human VIP-R-2
    MSDS:
    Please sign in first.
    ELISA Kit for Human VIP-R-2
    MSDS:
    Please sign in first.
    CLIA Kit for Human VIP-R-2
    MSDS:
    Please sign in first.
    CLIA Kit for Human VIP-R-2
    MSDS:
    Please sign in first.
    CLIA Kit for Human VIP-R-2
    Cat.:
    U15102h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human VIP-R-2
    Polyclonal Antibody for Human VIP-R-2
    Polyclonal Antibody for Human VIP-R-2
    Monoclonal Antibody for Human VIP-R-2
    Monoclonal Antibody for Human VIP-R-2
    Monoclonal Antibody for Human VIP-R-2
    Protein for Human VIP-R-2
    Protein for Human VIP-R-2
    Protein for Human VIP-R-2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and functional characterization of a human VIP receptor from SUP-T1 lymphoblasts."
      Svoboda M. , Tastenoy M. , van Rampelbergh J. , Goossens J.-F. , Neef P. , Waelbroeck M. , Robberecht P.
      Biochem. Biophys. Res. Commun.205:1617-1624(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1)
    2. 2.
      "Chromosomal localization in mouse and human of the vasoactive intestinal peptide receptor type 2 gene: a possible contributor to the holoprosencephaly 3 phenotype."
      Mackay M. , Fantes J. , Scherer S. , Boyle S. , West K. , Tsui L.-C. , Belloni E. , Lutz E. , van Heyningen V. , Harmar A.J.
      Genomics37:345-353(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Tissue specific expression of different human receptor types for pituitary adenylate cyclase activating polypeptide and vasoactive intestinal polypeptide: implications for their role in human physiology."
      Wei Y. , Mojsov S.
      J. Neuroendocrinol.8:811-817(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Adipose tissue.
    4. 4.
      "Structure of the human VIP2R gene for vasoactive intestinal peptide type 2 receptor."
      Lutz E.M. , Shen S. , Mackay M. , West K. , Harmar A.J.
      FEBS Lett.458:197-203(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1)
    5. 5.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    6. 6.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Heart.
    7. 7.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    10. 11.
      "Predominant expression of type II vasoactive intestinal peptide receptors by human T lymphoblastoma cells: transduction of both Ca2+ and cyclic AMP signals."
      Xia M. , Sreedharan S.P. , Goetzl E.J.
      J. Clin. Immunol.16:21-30(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 244-318 (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY
      tissue: T-cell.
    11. 12.
      "Crystal structure of the extracellular domain of human vasoactive intestinal polypeptide receptor 2."
      Structural genomics consortium (SGC)
      Submitted (2010-03) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 26-118;DISULFIDE BONDS
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